Photo of Ming Xu, Ph.D.

Ming Xu, Ph.D.

Assistant Professor, UConn Center on Aging and the Department of Genetics & Genome Sciences
Academic Office Location:
UConn Center on Aging
UConn Health
263 Farmington Avenue
Farmington, CT 06030-1835
Phone: 860-679-4338
Website(s):

Xu lab website

Genetics and Developmental Biology Graduate Program

Neuroscience Graduate Program

Please visit my lab website for more information.

https://mxuuconn.wixsite.com/xu-lab

 

Selected publications (#, corresponding  author; *, 1st author):

Xu M#, …, Kirkland JL#. “Senolytics Improve Physical Function and Increase Lifespan in Old Age.” Nature Medicine  2018 Aug;24(8):1246-1256. 

Wang B*, Wang L*, Gasek NS*, ..., Xu M#. “An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo” Nature Aging 2021; 1 (10), 962-973 

Gasek NS,Kuchel GA, Kirkland JL, Xu M#. “Strategies for Targeting Senescent Cells in Human Disease” Nature Aging 2021; 1 (10), 870-879

Wang L*, Wang B*, ..., Xu M#. “Targeting p21Cip1-Highly-Expressing Cells in Adipose Tissue Alleviates Insulin Resistance in Obesity” Cell Metabolism 2021  in press

Zhou Y, ..., Xu M#. “Senolytics improve the in vivo bone forming potential of bone marrow mesenchymal stem cells obtained from aged mice.” npj Regeneration Medicine, 2021 Jun 11;6(1):34.

Zhou Y, ..., Xu M#. “Senolytics alleviate the degenerative disorders of temporomandibular joint in old age.” Aging Cell, 2021 Jul;20(7):e13394

Wang B*, Liu Z*, ... Xu M#  "Transplanting cells from old but not young donors causes physical dysfunction in older recipients."  Aging Cell 2020 

Xu M, …, Kirkland JL. “JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.”  PNAS 2015 Nov17;112(46):E6301-10. 

Farr JN*, Xu M*, …Khosla S. “Causal Role of Senescent Cells in Mediating Age-Related Bone Loss.”  Nature Medicine 2017 Sep;23(9):1072-1079. 

 

 

Education
DegreeInstitutionMajor
B.S.Fudan UniversityBiological Science
Ph.D.University of Kansas Medical Center (KUMC)Rehabilitation Science

Post-Graduate Training
TrainingInstitutionSpecialty
Graduate Research AssistantUniversity of Kansas Medical CenterGraduate Research Assistant, Department of Physical Therapy and Rehabilitation Science, Dr. Hao Zhu’s Lab
FellowshipMayo ClinicResearch Fellow, Department of Internal Medicine, Dr. James L. Kirkland’s Lab
Research AssociateMayo ClinicResearch Associate, Department of Internal Medicine, Dr. James L. Kirkland’s Lab

Awards
Name of Award/HonorAwarding Organization
The 2023 Nathan Shock New Investigator Award, The Gerontological Society of America (GSA)GSA
Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty awardAFAR
Postdoctoral Transition Awards in AgingThe Irene Diamond Fund/AFAR
Career Development AwardRegenerative Medicine Initiative for Diabetes
Postdoctoral Fellowship Program for Translational Research on AgingGlenn/AFAR
Travel award, 2013 Alliance for Healthy Aging Symposium Held in the University Medical Center, Groningen, NetherlandsAlliance for Healthy Aging Symposium
Student Union Corporation Travel ScholarshipKUMC
Dean’s Diversity Scholarship, School of Allied HealthKUMC
School of Allied Health Scholarship AwardKUMC
First Place Award of Molecular and Cell Biology Session III Student Research ForumKUMC
Third Place Award, National Mathematics Contest (High School), China
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
NIH CMAD study sectionStudy Sectionstanding memberExternalNational2023
NIH U19 study sectionStudy SectionReviewerExternalNational20222022
AFAR National Scientific Advisory Council memberAdvisory CommitteeMemberExternalInternational2021
UCHC Biomedical Science Admissions CommitteeOtherMemberUConn HealthUniversity20212024
Ad hoc Reviewer for Scientific Journals (2012 - Present): Diabetes, Cell Metabolism, Aging Cell, FASEBJ, Trends in Endocrinology and Metabolism, Journal of Gerontology, Molecular and Cellular Biochemistry, Hormone and Metabolic ResearchProfessional/Scientific JournalAd hoc ReviewerExternalNational2012

Cellular senescence is one of the major players contributing to the fundamental aging process. My lab is leveraging novel mouse models and primary human cells as tools to examine the role and underlying mechanism of senescent cells in various conditions in mammals, and we aim to find new drugs to target senescent cells in order to alleviate a range of diseases as a group.



We have 3 major research directions.

1. To investigate the role of senescent cells in diseases. We are especially interested in diabetes, Alzheimer's disease, frailty, bone-related diseases, bladder dysfunction, and flu infection. We will be using novel transgenic mice and transplantation models for this.

2. To reveal the heterogeneity and transcriptomic signatures of senescent cells in vivo. We will be using single cell transcriptome technology to look at the senescent cells at different tissues under different biological conditions (aging, obesity or injury).

3. To screen for novel compounds to kill senescent cells. We are in the process of screening several libraries of compounds on human senescent cells, and expect to find a number of novel candidates. We will then further test these compounds in aged mice and human tissues.


 


 

We have several openings for graduate students and postdocs.

Accepting Lab Rotation Students: Summer 2023, Fall 2023, and Spring 2024

Lab Rotation Projects:
Within our research interest, a variety of different rotations can be designed based on individual trainee interests and background.



 


 

Journal Articles

  • SenNet recommendations for detecting senescent cells in different tissues.
    Suryadevara, Vidyani; Hudgins, Adam D; Rajesh, Adarsh; Pappalardo, Alberto; Karpova, Alla; Dey, Amit K; Hertzel, Ann; Agudelo, Anthony; Rocha, Azucena; Soygur, Bikem; Schilling, Birgit; Carver, Chase M; Aguayo-Mazzucato, Cristina; Baker, Darren J; Bernlohr, David A; Jurk, Diana; Mangarova, Dilyana B; Quardokus, Ellen M; Enninga, Elizabeth Ann L; Schmidt, Elizabeth L; Chen, Feng; Duncan, Francesca E; Cambuli, Francesco; Kaur, Gagandeep; Kuchel, George A; Lee, Gung; Daldrup-Link, Heike E; Martini, Helene; Phatnani, Hemali; Al-Naggar, Iman M; Rahman, Irfan; Nie, Jia; Passos, João F; Silverstein, Jonathan C; Campisi, Judith; Wang, Julia; Iwasaki, Kanako; Barbosa, Karina; Metis, Kay; Nernekli, Kerem; Niedernhofer, Laura J; Ding, Li; Wang, Lichao; Adams, Lisa C; Ruiyang, Liu; Doolittle, Madison L; Teneche, Marcos G; Schafer, Marissa J; Xu, Ming; Hajipour, Mohammadjavad; Boroumand, Mozhgan; Basisty, Nathan; Sloan, Nicholas; Slavov, Nikolai; Kuksenko, Olena; Robson, Paul; Gomez, Paul T; Vasilikos, Periklis; Adams, Peter D; Carapeto, Priscila; Zhu, Quan; Ramasamy, Ramalakshmi; Perez-Lorenzo, Rolando; Fan, Rong; Dong, Runze; Montgomery, Ruth R; Shaikh, Sadiya; Vickovic, Sanja; Yin, Shanshan; Kang, Shoukai; Suvakov, Sonja; Khosla, Sundeep; Garovic, Vesna D; Menon, Vilas; Xu, Yanxin; Song, Yizhe; Suh, Yousin; Dou, Zhixun; Neretti, Nicola. Nature Reviews Molecular Cell Biology. 2024 Jun;
  • Oscillatory Hypoxia Can Induce Senescence of Adipose-Derived Mesenchymal Stromal Cells Potentiating Invasive Transformation of Breast Epithelial Cells.
    Novin, Ashkan; Wali, Khadija; Pant, Aditya; Liu, Shaofei; Du, Wenqiang; Liu, Yamin; Wang, Lichao; Xu, Ming; Wang, Binsheng; Suhail, Yasir; Kshitiz Cancers 2024 Feb;16(5):
  • Unleashing CAR T cells to delay metabolic aging.
    Bartley, Jenna M; Xu, Ming Nature aging 2024 Feb;
  • TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential.
    He, Jing; Lin, Mingen; Zhang, Xinchao; Zhang, Ruonan; Tian, Tongguan; Zhou, Yuefan; Dong, Wenjing; Yang, Yajing; Sun, Xue; Dai, Yue; Xu, Yue; Zhang, Zhenru; Xu, Ming; Lei, Qun-Ying; Xu, Yanping; Lv, Lei Cell discovery 2023 Aug;9(1):84
  • Human rotator cuff tears demonstrate an age-dependent increase in markers of cellular senescence and selective removal of senescent cells with dasatinib+quercetin increases genetic expression of COL1A1 in vitro.
    Hawthorne, Benjamin C; Wellington, Ian J; Sabitsky, Joshua T; Murphy, Kyle V; Karsmarski, Owen P; Thomas, Rohin O; LeVasseur, Matthew R; Mancini, Michael R; Trudeau, Maxwell T; Gulati, Sagar; McCarthy, Mary Beth R; Cote, Mark P; Xu, Ming; Mazzocca, Augustus D Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2023 Jun;
  • Senescence-induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics.
    Lorenzo, Erica C; Torrance, Blake L; Keilich, Spencer R; Al-Naggar, Iman; Harrison, Andrew; Xu, Ming; Bartley, Jenna M; Haynes, Laura Aging cell 2022 Jan;e13525
  • Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity.
    Wang, Lichao; Wang, Binsheng; Gasek, Nathan S; Zhou, Yueying; Cohn, Rachel L; Martin, Dominique E; Zuo, Wulin; Flynn, William F; Guo, Chun; Jellison, Evan R; Kim, Taewan; Prata, Larissa G P Langhi; Palmer, Allyson K; Li, Ming; Inman, Christina L; Barber, Lauren S; Al-Naggar, Iman M A; Zhou, Yanjiao; Kuchel, George A; Meves, Alexander; Tchkonia, Tamar; Kirkland, James L; Robson, Paul; Xu, Ming. Cell Metabolism. 2021 Nov;
  • An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo
    Wang B, Wang L, Gasek NS, Zhou Y, Kim T, Guo C, Jellison ER, Haynes L, Yadav S, Tchkonia T, Kuchel GA, Kirkland JL, Xu M. Nature Aging 2021 Oct;1(10):962-973
  • Temporomandibular joint aging and potential therapies.
    Zhou, Yueying; Xu, Ming; Yadav, Sumit Aging 2021 Jul;undefined(undefined):
  • Senolytics improve bone forming potential of bone marrow mesenchymal stem cells from aged mice.
    Zhou, Yueying; Xin, Xiaonan; Wang, Lichao; Wang, Binsheng; Chen, Li; Liu, Ousheng; Rowe, David W; Xu, Ming NPJ Regenerative medicine 2021 Jun;6(1):34
  • Senolytics alleviate the degenerative disorders of temporomandibular joint in old age.
    Zhou, Yueying; Al-Naggar, Iman M A; Chen, Po-Jung; Gasek, Nathan S; Wang, Ke; Mehta, Shivam; Kuchel, George A; Yadav, Sumit; Xu, Ming Aging Cell. 2021 Jun;e13394
  • Transplanting cells from old but not young donors causes physical dysfunction in older recipients.
    Wang, Binsheng; Liu, Zukai; Chen, Vicky P; Wang, Lichao; Inman, Christina L; Zhou, Yueying; Guo, Chun; Tchkonia, Tamar; Rowe, David W; Kuchel, George A; Robson, Paul; Kirkland, James L; Xu, Ming Aging Cell. 2020 Jan;e13106
  • Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia.
    Suvakov, Sonja; Cubro, Hajrunisa; White, Wendy M; Butler Tobah, Yvonne S; Weissgerber, Tracey L; Jordan, Kyra L; Zhu, Xiang Y; Woollard, John R; Chebib, Fouad T; Milic, Natasa M; Grande, Joseph P; Xu, Ming; Tchkonia, Tamara; Kirkland, James L; Lerman, Lilach O; Garovic, Vesna D Biology of sex differences 2019 Sep;10(1):49
  • Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
    Palmer, Allyson K; Xu, Ming; Zhu, Yi; Pirtskhalava, Tamar; Weivoda, Megan M; Hachfeld, Christine M; Prata, Larissa G; van Dijk, Theo H; Verkade, Esther; Casaclang-Verzosa, Grace; Johnson, Kurt O; Cubro, Harjunisa; Doornebal, Ewald J; Ogrodnik, Mikolaj; Jurk, Diana; Jensen, Michael D; Chini, Eduardo N; Miller, Jordan D; Matveyenko, Aleksey; Stout, Michael B; Schafer, Marissa J; White, Thomas A; Hickson, LaTonya J; Demaria, Marco; Garovic, Vesna; Grande, Joseph; Arriaga, Edgar A; Kuipers, Folkert; von Zglinicki, Thomas; LeBrasseur, Nathan K; Campisi, Judith; Tchkonia, Tamar; Kirkland, James L Aging cell 2019 Mar;e12950
  • Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.
    Ogrodnik, Mikolaj; Zhu, Yi; Langhi, Larissa G P; Tchkonia, Tamar; Krüger, Patrick; Fielder, Edward; Victorelli, Stella; Ruswhandi, Rifqha A; Giorgadze, Nino; Pirtskhalava, Tamar; Podgorni, Oleg; Enikolopov, Grigori; Johnson, Kurt O; Xu, Ming; Inman, Christine; Schafer, Marissa; Weigl, Moritz; Ikeno, Yuji; Burns, Terry C; Passos, João F; von Zglinicki, Thomas; Kirkland, James L; Jurk, Diana Cell metabolism 2018 Dec;
  • Fisetin is a senotherapeutic that extends health and lifespan.
    Yousefzadeh, Matthew J; Zhu, Yi; McGowan, Sara J; Angelini, Luise; Fuhrmann-Stroissnigg, Heike; Xu, Ming; Ling, Yuan Yuan; Melos, Kendra I; Pirtskhalava, Tamar; Inman, Christina L; McGuckian, Collin; Wade, Erin A; Kato, Jonathon I; Grassi, Diego; Wentworth, Mark; Burd, Christin E; Arriaga, Edgar A; Ladiges, Warren L; Tchkonia, Tamara; Kirkland, James L; Robbins, Paul D; Niedernhofer, Laura J EBioMedicine 2018 Oct;3618-28
  • Senolytics improve physical function and increase lifespan in old age.
    Xu, Ming; Pirtskhalava, Tamar; Farr, Joshua N; Weigand, Bettina M; Palmer, Allyson K; Weivoda, Megan M; Inman, Christina L; Ogrodnik, Mikolaj B; Hachfeld, Christine M; Fraser, Daniel G; Onken, Jennifer L; Johnson, Kurt O; Verzosa, Grace C; Langhi, Larissa G P; Weigl, Moritz; Giorgadze, Nino; LeBrasseur, Nathan K; Miller, Jordan D; Jurk, Diana; Singh, Ravinder J; Allison, David B; Ejima, Keisuke; Hubbard, Gene B; Ikeno, Yuji; Cubro, Hajrunisa; Garovic, Vesna D; Hou, Xiaonan; Weroha, S John; Robbins, Paul D; Niedernhofer, Laura J; Khosla, Sundeep; Tchkonia, Tamara; Kirkland, James L Nature medicine 2018 Jul;241246-1256
  • Targeting cellular senescence prevents age-related bone loss in mice.
    Farr, Joshua N; Xu, Ming; Weivoda, Megan M; Monroe, David G; Fraser, Daniel G; Onken, Jennifer L; Negley, Brittany A; Sfeir, Jad G; Ogrodnik, Mikolaj B; Hachfeld, Christine M; LeBrasseur, Nathan K; Drake, Matthew T; Pignolo, Robert J; Pirtskhalava, Tamar; Tchkonia, Tamara; Oursler, Merry Jo; Kirkland, James L; Khosla, Sundeep Nature medicine 2017 Sep;23(9):1072-1079
  • Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.
    Xu, Ming; Bradley, Elizabeth W; Weivoda, Megan M; Hwang, Soyun M; Pirtskhalava, Tamar; Decklever, Teresa; Curran, Geoffry L; Ogrodnik, Mikolaj; Jurk, Diana; Johnson, Kurt O; Lowe, Val; Tchkonia, Tamar; Westendorf, Jennifer J; Kirkland, James L The journals of gerontology. Series A, Biological sciences and medical sciences 2017 Jun;72(6):780-785
  • 17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.
    Stout, Michael B; Steyn, Frederik J; Jurczak, Michael J; Camporez, Joao-Paulo G; Zhu, Yi; Hawse, John R; Jurk, Diana; Palmer, Allyson K; Xu, Ming; Pirtskhalava, Tamar; Evans, Glenda L; de Souza Santos, Roberta; Frank, Aaron P; White, Thomas A; Monroe, David G; Singh, Ravinder J; Casaclang-Verzosa, Grace; Miller, Jordan D; Clegg, Deborah J; LeBrasseur, Nathan K; von Zglinicki, Thomas; Shulman, Gerald I; Tchkonia, Tamara; Kirkland, James L The journals of gerontology. Series A, Biological sciences and medical sciences 2017 Jan;72(1):3-15
  • Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.
    Carpio, Lomeli R; Bradley, Elizabeth W; McGee-Lawrence, Meghan E; Weivoda, Megan M; Poston, Daniel D; Dudakovic, Amel; Xu, Ming; Tchkonia, Tamar; Kirkland, James L; van Wijnen, Andre J; Oursler, Merry Jo; Westendorf, Jennifer J Science signaling 2016 Aug;9(440):ra79
  • Targeting senescent cells enhances adipogenesis and metabolic function in old age.
    Xu, Ming; Palmer, Allyson K; Ding, Husheng; Weivoda, Megan M; Pirtskhalava, Tamar; White, Thomas A; Sepe, Anna; Johnson, Kurt O; Stout, Michael B; Giorgadze, Nino; Jensen, Michael D; LeBrasseur, Nathan K; Tchkonia, Tamar; Kirkland, James L eLife 2015 Dec;4e12997
  • JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.
    Xu, Ming; Tchkonia, Tamara; Ding, Husheng; Ogrodnik, Mikolaj; Lubbers, Ellen R; Pirtskhalava, Tamar; White, Thomas A; Johnson, Kurt O; Stout, Michael B; Mezera, Vojtech; Giorgadze, Nino; Jensen, Michael D; LeBrasseur, Nathan K; Kirkland, James L Proceedings of the National Academy of Sciences of the United States of America 2015 Nov;112(46):E6301-10
  • Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.
    Palmer, Allyson K; Tchkonia, Tamara; LeBrasseur, Nathan K; Chini, Eduardo N; Xu, Ming; Kirkland, James L Diabetes 2015 Jul;64(7):2289-98
  • Beta-Cell Injury in Ncb5or-null Mice is Exacerbated by Consumption of a High-Fat Diet.
    Guo, Ying; Xu, Ming; Deng, Bin; Frontera, Jennifer R; Kover, Karen L; Aires, Daniel; Ding, Helin; Carlson, Susan E; Turk, John; Wang, Wenfang; Zhu, Hao European journal of lipid science and technology : EJLST 2012 Mar;114(3):233-243
  • Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells.
    Wang, Wenfang; Guo, Ying; Xu, Ming; Huang, Han-Hung; Novikova, Lesya; Larade, Kevin; Jiang, Zhi-Gang; Thayer, Terri C; Frontera, Jennifer R; Aires, Daniel; Ding, Helin; Turk, John; Mathews, Clayton E; Bunn, H Franklin; Stehno-Bittel, Lisa; Zhu, Hao Biochimica et biophysica acta 2011 Nov;1812(11):1532-41
  • Ncb5or deficiency increases fatty acid catabolism and oxidative stress.
    Xu, Ming; Wang, WenFang; Frontera, Jennifer R; Neely, Melanie C; Lu, Jianghua; Aires, Daniel; Hsu, Fong-Fu; Turk, John; Swerdlow, Russell H; Carlson, Susan E; Zhu, Hao The Journal of biological chemistry 2011 Apr;286(13):11141-54
  • Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1.
    Zhang, Zhihong; Liao, Bing; Xu, Ming; Jin, Ying FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Oct;21(12):3042-51
  • Inferring population history from fine-scale spatial genetic analysis in Oryza rufipogon (Poaceae).
    Xu, Xian; Lu, Bao-Rong; Chen, Yolanda H; Xu, Ming; Rong, Jun; Ye, Pingyang; Chen, Jiakuan; Song, Zhiping Molecular ecology 2006 May;15(6):1535-44
  • NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
    Brown University TDA Wang Siyuan (Steven) 34, Columbia TMC Bonneau Richard 39 40 Christiano Angela 41 Izar Benjamin 42 Menon Vilas 43 Owens David M. 44 Phatnani Hemali 43 Smith Colin 45 Suh Yousin 41 Teich Andrew F. 43, Duke University TMC Bekker Valerie 1 Chan Cliburn 32 Coutavas Elias 1 Hartwig Matthew G. 46 Ji Zhicheng 32 Nixon Andrew B. 19, Massachusetts General Hospital TDA Dou Zhixun 47 Rajagopal Jayaraj 47 Slavov Nikolai 48, Mayo Clinic TDA Holmes David III 13 Jurk Diana 13 Kirkland James L. 49 Lagnado Anthony 13 Tchkonia Tamara 13, National Institute of Health (NIH) Abraham Kristin 50 Dibattista Amanda 51 Fridell Yih-Woei 17 Howcroft T. Kevin 52 Jhappan Chamelli 53 Montes Viviana Perez 17 Prabhudas Mercy 54 Resat Haluk 55 Taylor Veronica 30, Stanford TDA Kumar Manoj 6 Suryadevara Vidyani 6, University of Michigan TDA Assarzadegan Naziheh 58 Cho Chun-Seok 20 Hwang Irene 20 Hwang Yongha 20 Xi Jingyue 59, University of Washington TDA Gu Liangcai 73 Lin Yiing 74 Rabinovitch Peter S. 75 Sweetwyne Mariya T. 75, Yale TMC Craft Joseph E. 86 Enninful Archibald 11 Farzad Negin 11 Gershkovich Peter 87 Halene Stephanie 88 Kluger Yuval 87 VanOudenhove Jennifer 89 Xu Mina 87 Yang Junchen 87 Yang Mingyu 11 Nature aging
  • Role of Senescent Cells in Cutaneous Wound Healing
    AM Andrade, M Sun, NS Gasek, GR Hargis, R Sharafieh, M Xu Biology
  • Senolytic treatment with dasatinib and quercetin does not improve overall influenza responses in aged mice
    Blake L Torrance, Andreia N Cadar, Dominique E Martin, Hunter A Panier, Erica C Lorenzo, Jenna M Bartley, Ming Xu, Laura Haynes Front. Aging

Book Chapters

  • Inflammation and Aging
    Xu M, Kirkland JL Handbook of Theories of Aging, Third Edition 2016 Jan;137-152

Reviews

Title or AbstractTypeSponsor/EventDate/YearLocation
Targeting Cellular Senescence to Alleviate Age-Related DiseaseLectureSystems Biology of Aging2019Farmington, CT
NIA Workshop on Repurposing Drugs or Dietary Supplements for their Senolytic or Senomorphic effects“Ruxolitinib and other JAK-inhibitors as modulators of the senescence- associated secretory phenotype”Panel DiscussionNIA Workshop2019Bethesda, MD
Senescence and SenolyticsPanel DiscussionU13 Bench-to-Bedside Conference Series Osteoporosis and Soft Tissue2019Bethesda, MD
Targeting cellular senescence to alleviate age-related diseasesLectureKUMC2018Kansas City
Targeting cellular senescence to alleviate age-related diseasesLectureUConn Storrs2018Storrs
Blocking the senescence-associated secretory phenotype (SASP) reduces osteoclastogenesis and prevents age-related bone lossPosterAmerican Society for Bone and Mineral Research 2015 Annual Meeting2015Seattle
The role of cellular senescence in age-related tissue dysfunction and diseasesPosterPaul F. Glenn/AFAR Conf on Biology of Aging 28th Annual AFAR Grantee Conf.2015Santa Barbara
The bystander and systematic adverse effects of senescent preadipocytesPosterExperimental Biology 20142014San Diego
Local and systematic adverse effects of senescent preadipocytesPosterGerontological Society of America Annual Scientific Meeting 20132013New Orleans
Local and systematic adverse effects of senescent preadipocytesPosterAlliance for Healthy Aging Symposium2013University Medical Center, Groningen, Netherlands
Local and systematic adverse effects of senescent preadipocytesPosterGordon Research Conference (GRC) on Biology of Aging2013Lucca (Barga), Italy
Senescent cells compromise fat tissue functionsPoster3rd Ann. Robert & Arlene Kogod Ctr on Aging Conf: Senescence & Healthspan2012Mayo clinic
Senescent cells compromise fat tissue functionsPanel DiscussionIntern. Federation for Adipose Therapeutics and Science, 10th Ann. Meeting2012Québec City, Canada
Ncb5or deficiency increases fatty acid catabolism and oxidative stressPoster2011 Liver Symposium, The Liver Center, Univ. of Kansas Medical Center2011Kansas City, Kansas
Ncb5or deficiency increases fatty acid catabolism and oxidative stressPosterAnn. Mtg of American Soc. for Biochem. and Molecular Biology (Exp. Biol.)2011Washington, D.C.
Ncb5or deficiency increases fatty acid catabolism and oxidative stressPanel DiscussionStudent Research Forum, Univ. of Kansas Medical Center2011Kansas City, Kansas
Defect in fatty acid desaturation leads to lipoatrophy through mitochondrial over-proliferation and compensation from de novo synthesis in Ncb5or null miceTalkStudent Research Forum, Univ. of Kansas Medical Center2009Kansas City, Kansas
Fatty acid metabolism, diabetes and lipoatrophy in Ncb5or knockout micePosterStudent Research Forum, Univ. of Kansas Medical Center2008Kansas City, Kansas