Photo of Erin E. Young, Ph.D.

Erin E. Young, Ph.D.

Assistant Professor of both School of Nursing and Genetics and Developmental Biology.
Academic Office Location:
School of Nursing and Gen. Dev. Biology
University of Connecticut / UCONN Health Center
231 Glenbrook Rd. / 263 Farmington Ave.
Unit 4026
Storrs / Farmington, CT 06269 / 06030
Phone: 860-486-2852

Genetics & Developmental Biology Graduate Program

B.A.Wesleyan CollegeBiology
M.A.Kent State UniversityExperimental Biological Psychology
Ph.D.Kent State UniversityExperimental Biological Psychology

Post-Graduate Training
PostdoctoralCo-Investigator/Mentor for Carrie Ellen Briere
Graduate Student, Ph.D.Co-Advisor for Dissertation/GA advisor for Amy D'Agata
Graduate Student, Ph.D.Major Advisor for Carrie Eaton

Name of Award/HonorAwarding Organization
Foreign Travel AwardInternational Association for the Study of Pain
Teaching ExcellenceStudent Recognition Award
(CARE) Committee on Animal Research and Ethics, Imprinting-Interdivisional Mentoring Fellowship AwardAmerican Psychological Association
Dissertation Research AwardAmerican Psychological Association
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Kent State University: President, Graduate Association of Students in PsychologyEducation CommitteeMemberExternalUniversity20042005
Kent State University: Graduate Student SenateEducation CommitteeMemberExternalUniversity20032004
Kent State University: Experimental Training Committee MemberEducation CommitteeMemberExternalUniversity20022003
International Association for the Study of PainProfessional/Scientific OrganizationMemberExternalInternational
American Pain SocietyProfessional/Scientific OrganizationMemberExternalNational
Society for NeuroscienceProfessional/Scientific OrganizationMemberExternalNational
Persistent pain in inflammatory bowel disease: utilizing a bedside-to-bench-to-bedside approach to understand the mechanisms underlying chronic visceral pain [Grand Rounds, October 2013. Connecticut Children’s Medical Center, Hartford, CT].Professional/Scientific OrganizationMemberExternalState2013
Genetics of pain: Pathway to personalized medicine [April 2014, 2nd Joint Symposium of IHS/IASP, Siena, ITALY].Professional/Scientific OrganizationMemberExternalInternational2014
The genetics of persistent bowel pain: Findings from mouse models suggest novel therapeutic targets. [Translational Research Seminar Series, September 2014. Hartford Hospital/Connecticut Children’s Medical Center, Hartford, CT].Professional/Scientific OrganizationMemberExternalState2014
Urogenital pain syndromes: Using rodent models to understand comorbidity, novel targets and treatments. [May 2015. Symposium (Accepted), Annual Scientific Meeting of the American Pain Society, Palm Springs, CA].Professional/Scientific OrganizationMemberExternalNational2015
Professional ad hoc reviewerOtherReviewerNational
Professional ad hoc reviewerOtherReviewerNational
Professional ad hoc reviewerOtherReviewerNational
Grant reviewerOtherReviewerNational
Grant reviewerOtherReviewerNational

My primary interest lies in the understanding of gene x environment interactions on pain outcomes, with a particular focus on stress and injury/inflammation as environmental factors. Genetic factors have been shown to contribute significantly to variability in the response to painful stimuli. We are beginning to unravel the individual gene candidates and the families of genes that contribute to differences in pain responses. Using genetic correlation analysis with standard inbred strains of mice in addition to whole-genome quantitative trait locus (WTL) mapping with genetic reference populations as our most powerful tools, we are able to explore the genetic contribution to both somatic and visceral pain behaviors. Stress and inflammation can both modulate pain responses to various stimuli, and it is likely that different genes are involved in pain under normal conditions and the modulation of pain through environmental factors. Most recently, my research has focused on these issues as they relate to bowel pain after inflammation using animal models of Inflammatory Bowel Disease (IBD). The candidate genes identified in preclinical models can then be examined in clinical populations to determine whether these genes contribute to pain susceptibility in IBD patients. The goal is to further understand the mechanisms underlying persistent bowel pain and to use this knowledge to identify novel therapeutic targets to reduce pain and suffering in clinical populations.


Journal Articles